ARTICLE
Comparison of careHPV and Hybrid Capture 2 Assays for Detection of High-Risk Human Papillomavirus DNA in Cervical Samples from HIV-1-Infected African Women
- Journal of clinical microbiology , 51 (12) : 4240-4242
Lien de l'article :
https://doi.org/10.1128/jcm.02144-13
Discipline :
Sciences biologiques
Auteur(s) :
Jean Ngou, Mahlape P Magooa, Clare Gilham, Florencia Djigma, Marie-Noelle Didelot, Helen Kelly, Albert Yonli, Bernard Sawadogo, David A Lewis, Sinead Delany-Moretlwe, Philippe Mayaud, Michel Segondy
Auteur(s) tagués :
SIMPORE Jacques
Renseignée par : DJIGMA Wendkuuni Florencia
Résumé
The careHPV and HC2 assays were compared for high-risk human papillomavirus (HR-HPV) DNA detection in cervical samples from 149 HIV-1-infected African women. The HR-HPV DNA detection rates were 37.6% and 34.9% for careHPV and HC2, respectively. Agreement between the two tests was 94.6% (95% confidence interval [CI], 89.7% to 97.7%) with a kappa value of 0.88 (95% CI, 0.81 to 0.96), indicating an excellent agreement. careHPV may be considered as suitable as HC2 for cervical cancer screening among HIV-infected African women.
Mots-clés
careHPV; Hybrid Capture 2 Assays; HR-HPV; Comparison