Phytochemical screening, antioxidant and anti-edematous activities of aqueous extract of Sarcocephalus latilolius (sm.) Bruce ripe fruits in rat

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Résumé

Extract at 10 mg/mL yielded 92.95±11.44 mg EAG/g total polyphenols, 0.082±0.005 mg ERu/g total flavonoids and 0.14 ± 0.003 mg EAT/g condensed tannins. Aqueous extract of Sarcocephalus latifolius ripe fruits showed DPPH radical inhibition with an IC50 greater than 25 μg/mL. DPPH inhibition by gallic acid was 92.91% at 25 μg/mL. IC50 of ascorbic acid and aqueous extract of Sarcocephalus latifolius on Fe3+reducing antioxidant power (FRAP) were 18.9 μg/mL and 111.6 μg/mL, respectively. For carrageenan, the aqueous extract of Sarcocephalus latifolius ripe fruits
showed a maximal anti-inflammatory effect at five hours, with inhibitions (p

Mots-clés

Antioxidant; Anti-inflammatory; Sarcocephalus latifolius fruits; Rats