Distribution and Incidence of Blood-Borne Infection among Blood Donors from Regional Transfusion Centers in Burkina Faso: A Comprehensive Study

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Résumé

Abstract. There is a high prevalence of blood-borne infections in West Africa. This study sought to determine the
seroprevalence of blood-borne infections, including hepatitis B virus (HBV), hepatitis C virus (HCV), HIV, and syphilis, in
blood donors in Burkina Faso. Blood donors were recruited from 2009 to 2013 in four major cities in Burkina Faso of urban
area (Ouagadougou) and rural area (Bobo Dioulasso, Fada N’Gourma, and Ouahigouya). Serology tests including hepatitisBsurface
antigen, anti-HCV, anti-HIV, and rapid plasma reagin test were used for screening and were confirmed with
ELISA. Disease prevalence was calculated among first-time donors. Incidence and residual risk were calculated from
repeat donors. There were 166,681 donors; 43,084 had ³ 2 donations. The overall seroprevalence of HBV, HCV, HIV, and
syphilis were 13.4%, 6.9%, 2.1%, and 2.4%, respectively. The incidence rates (IRs) of HBV, HCV, HIV, and syphilis
infection were 2,433, 3,056, 1,121, and 1,287 per 100,000 person-years. There waslower seroprevalence ofHBVandHCV
in urban area than in rural area (12.9% versus 14.0%, P

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